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THE FEATURES OF TREATMENT OF CHRONIC COLPITIS IN THE WOMEN WITH DIABETES

THIS ARTICLE PRESENTS THE RESULTS OF TREATMENT OF CHRONIC COLPITIS CAUSED BY CAND >DIABETES MELLITUS TYPE 1 AND TYPE 2. THE OBJECTIVE OF THIS STUDY IS TO PROVE THE EFFECTIVENESS OF AN INTEGRATED APPROACH TO TREATMENT (LOCAL THERAPY COMBINED WITH SYSTEMIC MEDICATIONS AND IMMUNOMODULATOR THE POLYOXIDONY IN RECURRENT COLPITIS). AT DIABETES THE INCREASE OF GLUCOSE IN THE URINE AND VAGINAL EPITHELIAL CELLS, BUT THE DEGENERATION OF THE LATTER ARE OBSERVED. SUBSTRATE FOR THE SUPPLY OF BACTERIA IS SECRETED THE VAGINAL GLYCOGEN THAT PROMOTES BREEDING YEASTS, THEIR INTRODUCTION INTO THE CELLS OF THE EPITHELIUM AND ITS DESTRUCTION WITH THE FORMATION OF EROSIONS. THE AUTHORS NOTED THAT CHRONIC COLPITIS COMBINED WITH DIABETES MELLITUS OFTEN GIVES RELAPSE AFTER TREATMENT. THERAPY BY MEANS OF THE POLYOXIDONY ALLOWS TO CORRECTE QUICKLY AND EFFICIENTLY THE IMMUNOLOGICAL DISORDERS, TO NORMALIZE QUICKLY CARBOHYDRATE METABOLISM AND TO ARREST EFFECTIVELY THE CLINICAL SYMPTOMS OF VAGINITIS. CLINICAL AND IMMUNOLOGICAL EFFECTS PERSIST FOR AT LEAST 6 MONTHS.

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10. Ku, C.F. Total thyroidectomy replaces subtotal thyroidectomy as the preferred surgical treatment for Graves' disease / Ku C.F., Lo C.Y., Chan W.F. // ANZ J. Surg.- 2005.- Vol. 75.- N 7.- P. 528-531.

11. Moalem, J. Treatment and prevention of recurrence of multinodular goiter: an evidence-based review of the literature / J.Moalem, I.Suh, Q.Y. Duh // World J. Surg.- 2008.- Vol. 32.- N 7.- P. 1301-1312.

12. Palit, T.K. The efficacy of thyroidectomy for Graves' disease: A meta-analysis / T.K.Palit, C.C. Miller, D.M. Miltenburg // J. Surg. Res.- 2000.- Vol. 90.- N 2.-P. 161-165.

13. Phitayakorn, R. Follow-up after surgery for benign nodular thyroid disease: evidence-based approach / R.Phitayakorn, C.R. McHenry // World J. Surg.- 2008.-Vol.32.- N 7.- P. 1374-1384.

14. Snook, K.L. Recurrence after total thyroidectomy for benign multinodular goiter / K.L. Snook// World J. Surg.- 2007.- Vol. 31.- N 3.- P. 593-598.

15. Tezelman, S. The change in surgical practice from subtotal to near-total or total thyroidectomy in the treatment of patients with benign multinodular goiter /

S.Tezelman, I.Borucu, Y. Senyurek // World J. Surg.-2009.- Vol. 33.- N 3.- P. 400-405.

16. Vaiman, M. Subtotal and near total versus total thyroidectomy for the management of multinodular goiter / M.Vaiman, A.Nagibin, P.Hagag // World J. Surg.-2008.- Vol.32.- P. 1546-1551.

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THE FEATURES OF TREATMENT OF CHRONIC COLPITIS IN THE WOMEN WITH DIABETES

I.N. KOROTKIH, T.V. ANISIMOVA, V.Y. BRIGADIROVA

Voronezh State N.N. Burdenko Medical Academy

Abstyract: this article presents the results of treatment of chronic colpitis caused by Candida albicans in the women with diabetes mellitus type 1 and type 2. The objective of this study is to prove the effectiveness of an integrated approach to treatment (local therapy combined with systemic medications and immunomodulator the Polyoxidony in recurrent colpitis). At diabetes the increase of glucose in the urine and vaginal epithelial cells, but the degeneration of the latter are observed. Substrate for the supply of bacteria is secreted the vaginal glycogen that promotes breeding yeasts, their introduction into the cells of the epithelium and its destruction with the formation of erosions. The authors noted that chronic colpitis combined with diabetes mellitus often gives relapse after treatment. Therapy by means of the Polyoxidony allows to correcte quickly and efficiently the immunological disorders, to normalize quickly carbohydrate metabolism and to arrest effectively the clinical symptoms of vaginitis. Clinical and immunological effects persist for at least 6 months.

Key words: chronic colpitis, diabetes mellitus , Polyoxidony, Candida albicans.

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